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AOD9604 Phase IIb obesity trial results and program termination announcement

DOI: 10.3390/ijms19103041

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Because melanin helps absorb UV radiation, higher melanin levels can also increase the skins natural UV resilience, meaning some people may notice less tendency to redden with the same sun exposure

Native IGF-1 exists as an FDA-approved human drug: recombinant human IGF-1, marketed as mecasermin (brand name Increlex), is approved for the treatment of growth failure in children with severe primary IGF-1 deficiency and in patients who have developed neutralizing antibodies to growth hormone

Women who are pregnant or planning to become pregnant should avoid this medication unless clearly needed, due to unknown fetal risks