The solubility score based on the Protein-Sol web server was computed to be 0.796, 0.801, and 0.821 (cutoff: 0.45) for nGLP1-DARPin, mGLP1-DARPin-1, and mGLP1-DARPin-2, respectively
Acknowledgments I thank Lily Lu, MD, PhD for her critical comments and David Liu and Erika Liu for their assistance with editing
NASH, Nonalcoholic steatohepatitis
Structural Characterization of GLP-1 Analogues and Formulations Using Microfluidic Modulation Spectroscopy Abstract Glucagon-like peptide-1 (GLP-1) analogues, such as semaglutide and liraglutide, are widely used in treating obesity and type 2 diabetes due to their enhanced stability and prolonged half-life
The Biochemical journal 238, 345351 (1986)
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