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These shifts in prescribing, regarding choice of substance and brand, could partially be explained by the recommendations issued by the Drug and Therapeutics Committee in Region Stockholm (Kloka listan) [62] and the year of market introductions of Ozempic and Rybelsus

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hence, GLP-1 agonists could be started in primary or secondary care

Experimental research shows that weight loss induced by caloric restriction or exercise primarily increases total ghrelin by raising plasma levels of des-acyl ghrelin, rather than acylated ghrelin, in individuals with overweight or obesity [44]

As of 2021, 11.6% of the U.S