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A systematic review in 2025 identified one qualifying clinical study: a retrospective analysis in which 7 of 12 subjects with chronic knee pain reported relief for over six months following intra-articular injection

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Suppression of the phenotype of gamma(1)34.5- herpes simplex virus 1: failure of activated RNA-dependent protein kinase to shut off protein synthesis is associated with a deletion in the domain of the alpha47 gene