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Visit our Manitoba Ozempic page for more information

GLP-1 Pathway Shared with Ozempic Reduces appetite via hypothalamic signaling Slows gastric emptying (delays food leaving stomach) Stimulates glucose-dependent insulin secretion Suppresses glucagon release (reduces liver glucose output) Improves satiety and reduces food intake GIP Pathway Unique to Mounjaro Enhances insulin sensitivity in adipose tissue Improves fat metabolism and lipid handling Reduces fat storage in visceral depots Boosts energy expenditure (thermogenesis) Synergizes with GLP-1 for amplified weight loss Combined Effects on the Body Clinical Evidence SURMOUNT Clinical Trial Results Tirzepatide has the strongest evidence base of any weight loss medication ever studied

Serious side effects are rare but can include pancreatitis

Severe vomiting lasting more than 3 days, signs of dehydration (dark urine, dizziness, extreme thirst), or persistent abdominal pain beyond week 2 should prompt a conversation with your PlexusDx provider

Patients interested in participating in research should speak with their healthcare team about potential clinical trials

Fortunately, the abdomen and thighs are great alternatives that allow for easy and safe self-administration