Future research should focus on developing and optimizing methods that can integrate multiple omics data to gain a more comprehensive understanding of the pathophysiological mechanisms of OA and to facilitate the development of new therapeutic approaches
6 Future directions Despite growing evidence supporting the cardiovascular benefits of GLP-1 receptor agonists, current research remains limited by heterogeneity in study design, variability in drug class and treatment duration, and the absence of standardized plaque-level mechanistic assessments
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