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Efficacy and safety of LixiLan, a titratable fixed-ratio combination of insulin glargine plus lixisenatide in type 2 diabetes inadequately controlled on basal insulin and metformin: the LixiLan-L randomized trial

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In the United States, where there had not been an anti-obesity drug approved by the FDA since 2014, Wegovy (semaglutide), a once-weekly injection was approved in June 2021

Semaglutide significantly reduces appetite, making it easier to maintain a caloric deficit without extreme restriction

Melanoma may also occur in mucous membranes (thin, moist layers of tissue that cover surfaces such as the lips)

Note: It is not recommended for Type 1 diabetes or diabetic ketoacidosis