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Based on these results, scientists at Tokushima University Hospital and Suzuka University of Medical Science, in Japan, conducted a long-term Phase 2/3 clinical trial (NCT00444613) to evaluate the efficacy and safety of ultra-high-dose methylcobalamin treatment for ALS

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Therapies that increase the breakdown of fatty acids in the liver or lower the amount of VLDL in the blood (like fibrate drugs or high-dose niacin) 67 also result in lower serum cholesterol levels

All three significantly altered factors were cytokines in the IL-17 family (IL-17A, IL-17B, IL-17D) ( Figures 8AC )

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