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Nature (2019) 572(7770):E20

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Arkin AP, Schaffer DV

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Mechanistically, two major NETosis phenotypes have been delineated: (1) Suicidal NETosis, a slower and oxidant-dependent pathway that culminates in plasma membrane rupture and neutrophil death, and (2) Vital NETosis, a rapid, non-lytic process in which neutrophils remain functionally active, capable of migration, phagocytosis, and cytokine secretion following NET release [47]

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