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Furthermore, ketamine has also been shown to inhibit activity of the default mode network (DMN ) in the brain, portions of the brain that are active when the mind is believed to be at rest, i.e
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Biol 2006, 288A, 91103
The synergy arises from the convergence of two independent second messenger systems cAMP/PKA from GHRHR and phospholipase C/calcium from GHS-R1a at the level of GH vesicle exocytosis
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