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Growth hormone secretagogues, like those studied in the CJC-1295/Ipamorelin research guide, target the GH/IGF-1 axis rather than incretin pathways and may be studied alongside GLP-1 class compounds for their complementary effects on body composition

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As a class, GLP-1RAs were also seen to reduce all-cause mortality by 11% compared to placebo [54]

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A graded glucose infusion test (GGIT) assessed insulin secretion rate (ISR) in treated participants and a group of untreated healthy participants

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