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Typical protocols involve a series of weeks on the peptide, followed by a rest period where the peptide isnt administered

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Benfenati E, Gini G, Hoffmann S and Luttik R 2010 Comparing in vivo , in vitro and in silico methods and integrated strategies for chemical assessment: Problems and prospects

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This neuroprotective form of APP contrasts with the pathogenic amyloid-beta fragments that are implicated in Alzheimers disease