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Cycling sermorelin comes from a misunderstanding of its pharmacology, often reinforced by old habits from bodybuilding forums where 5:2 (5 days on: 2 days off) dosing schedules were more about saving money than improving outcomes

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There is evidence that mitochondrial respiratory complex activity and mitochondrial membrane potential decline during aging and that endogenous antioxidant system activities exhibit an age-dependent decrease, making redox imbalance play a more predominant role in the aged cells and tissues

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Efficacy-wise, AOD-9604 produces modest results (2-3 kg over 12 weeks in trials) compared to GLP-1 agonists dramatic weight loss