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The crude product was purified by a silica gel column chromatography using hexane and dichloromethane mixture (10:1 v/v) as eluent and obtained as yellow powder in 74% yield

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The disproportionate analyses conducted concurrently with our study, based on the FAERS database with varying year spans, also indicate no direct association between GLP-1RAs and SSIBs [55, 56]