Doxorubicins localized, high-affinity binding highlights key pharmacophores for inhibitor design, while -carotenes broad, hydrophobic engagement supports strategies for developing allosteric modulators with reduced cytotoxic potential
The Harris lab is supported by the UW Department of Surgery, School of Medicine and Public Health, Wisconsin Alumni Research Fund, and the Office of the Vice Chancellor for Research
Any consideration of GLP-1 therapy should involve comprehensive evaluation by an endocrinologist or appropriate specialist, with clear discussion of the investigational nature of this approach, potential risks, costs, and the importance of ongoing monitoring
The transcobalamin II-cobalamin (TCN2-cobalamin) complexes are taken up, from the blood, by all cells via a plasma membrane transcobalamin receptor (TCBLR) encoded by the CD320 gene
She points to another type of common skin cancer, squamous cell carcinoma, which is thought to be due to cumulative UV exposure
(2019) Targeting MTHFR for the treatment of migraines