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J Clin Endocrinol Metab 105:E963972

They are NOT for use as food additives, drugs, cosmetic, household chemicals, or other inappropriate applications

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Because compounded drugs do not have the guardrails, nor have they been tested in large populations, there are risks associated with them, and they therefore should never be produced on a mass marketing basis except in very limited situations where the FDA has declared a shortage of drugs in high demand

One article pointed out that more than ~2% for SH might risk drying in very arid conditions