C.ImpagnatielloF.et al (2013)
doi: 10.1080/15592324.2017.1356970 115 RahmanM
However, C4 levels in IBS-D are not significantly correlated to mucosal permeability as assessed by urinary excretion of lactulose/mannitol, and in 23 patients with IBS-D, treatment with colesevelam tended to improve stool consistency but did not alter mucosal permeability as assessed by lactulose/mannitol excretion (173)
10.1016/J.ENCECO.2025.10.014 146 LockmanP
However, it should be used cautiously and discussed with the health care provider in the following conditions: -Pregnant and breastfeeding women -Liver impairment -Renal issues -Seizures References Nasca C, Bigio B, Lee FS, et al
Before you start using Ozempic, talk with your doctor if any of the preceding factors apply to you