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Obesity is a significant modifier of disease severity and recurrence risk

Studies show MT-II reduces food intake in a dose-dependent manner and leads to sustained body mass reduction and lower adiposity, even after appetite normalizes (5)

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Structured wraparound care is expected to accelerate adoption

SHU-9119 is the same MT-II scaffold with D-2-naphthylalanine substituted at position 7, a single change that converts it from a full agonist into an MC3R and MC4R antagonist while remaining an agonist at MC1R and MC5R