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Efficient GST activity and adequate glutathione are thus important for neutralizing patulin.[ref] Overall, combinations of slower CYP1A2/CYP3A4 alleles with reduced-function GST or UGT variants can leave someone more vulnerable at normal dietary exposure levels, because reactive mycotoxin intermediates may not be cleared efficiently

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Using a tree shrew model, we also observed a significantly increased level of 8-OHdG in all HCV-infected tree shrews compared to that in control tree shrews 56