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For instance, it has been shown that after an experimental psychologic stress, the evoked cortisol response in fatigued breast cancer survivors is much smaller than that in nonfatigued ones, pointing to the involvement of the HPA axis in cancer-related fatigue (286)

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Tales inconvenientes pueden alcanzar a ms del 50 % de los pacientes, aunque afortunadamente suelen ser transitorios y ocurren sobre todo al inicio del tratamiento