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Comment: Several commenters requested, as an alternative to our proposal to replace the estimated allowed amount with the median allowed amount and to add the 10th and 90th percentile allowed amounts, that CMS require hospitals, without exception, to make public all their payer-specific negotiated charges in dollars and cents, thus eliminating the need for the currently required estimated allowed amount or the proposed median, 10th percentile, and 90th percentile allowed amounts

This consistency is essential for reproducible research outcomes across multiple studies or study sites

Very cold storage, repeated movement between cold and warmer environments, shaking, unsuitable solvent conditions, or high concentration can all increase the chance of visible changes

Macromolecules 53, 91589186

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