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Although a 10-15% weight reduction is significant, it often falls short of the degree of weight loss required to achieve disease resolution in the morbidly obese

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Outcomes in cardiometabolic risk GLP1R expression has been detected at low levels in human atria and ventricles, both in cardiomyocytes and endothelial cells, though its precise localization remains unclear due to limitations in antibody specificity and differences at species level [93]