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Early-stage thinning with mostly intact follicles responds better than advanced loss where follicles have been miniaturized for years

It is also utilized in the treatment of various conditions such as Parkinson's disease, Alzheimer's disease, and cancer

Kazemi S, Hanachi P, Zivary S, Kasmaie A, Walker TR, Goshtasbi H

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Moreover, rats treated with 1% neohesperidin dihydrochalcone for 1 month showed reduced amygdala neuroinflammation via suppression of cAMP/PKA pathway activity, restoration of cortical 5-HT, DA, and NE levels, and reversal of anxiety- and depression-like behaviors (Jiang et al., 2023)