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Design The trial followed a randomized, double-blind, placebo-controlled, crossover design with two arms (ClinicalTrials.gov, NCT05733364, 19.01.2023)

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Ethics declarations Ethics approval and consent to participate The South Eastern Sydney Local Health District Human Research Ethics Committee [13/023 (HREC/13/POWH/65)] and the Animal Care and Ethics Committee (ACEC15/106A) of The University of New South Wales, Sydney, Australia, approved the studies in this manuscript