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The peptides appear to work through different mechanisms, with BPC-157 affecting angiogenesis and growth factor expression while IGF1 LR3 directly starts IGF-1 receptors

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Large clinical trials such as the STEP 1 trial demonstrated no increased thyroid cancer incidence over 68 weeks

A 2024 study in Brain, Behavior, & Immunity - Health identified severe CD8 T-cell dysfunction in both ME/CFS and Long COVID patients, linking this immune exhaustion directly to mitochondrial failure

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