These agents promote urinary glucose excretion, leading to reductions in HbA1c, body weight, and blood pressure, with proven cardiovascular and renal protection
NHS access requires meeting NICE eligibility criteria, specialist or enhanced GP assessment, and demonstration of metabolic response (HbA1c reduction 11 mmol/mol and 3% weight loss) at six months
The lower achievement rates may be attributed to the effects of concomitant antidiabetic drugs, as demonstrated in PIONEER 3 study, as well as the potential presence of insulin resistance resulting from chronic poor glycemic control
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As retatrutide is an investigational medicine, any adverse events must be reported through your trial's reporting pathway in line with the study protocol