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Published data from TRIUMPH-1 and TRIUMPH-4 show that discontinuation rates rise with dose

These findings highlight the potential of GLP-1 agonists in MASLD/MASH management, warranting further prospective studies

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Any episode of syncope (loss of consciousness) requires immediate medical assessment, as this may indicate significant hypotension or other serious conditions requiring investigation

The recommended approach is to restart one dose tier below your maintenance level, hold for two weeks, then resume your target dose

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