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For adults, the typical dose is 325 mg to 1000 mg every 4 to 6 hours, not exceeding 4000 mg per day

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However, these models are poor substitutes for in vivo models of atherosclerosis that involve different stimuli, immune populations, and timing

Plant Soil Environ 63:271276 Spoorthi N, Kavyashree NM, Sushma V, Vijayaraghavareddy P, Sreeman S (2025) Warm Nights, waxy leaves: exploring the interplay between epicuticular wax and nocturnal transpiration

It has been reported that in the critical phase of COVID-19, vitamin C plays a serious role in downregulating the cytokine storm, thus supporting tissue repair and improving immune responses against infections