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In a murine model of bacterial pneumonia, luteolin demonstrated the capacity to inhibit M1 macrophage polarization by suppressing the EGFR/PI3K/AKT/NF-B and EGFR/ERK/AP-1 signaling pathways

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Therefore, those patients benefitted from the supplementation of the vitamin B12

Pi-Sunyer X, Astrup A, Fujioka K et al (2015) A randomized, controlled trial of 30 mg of liraglutide in weight management