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Immunohistochemical analysis also revealed a significant decrease in the hepatic expression of both proapoptotic markers Bax and caspase-3 with significant increase in antiapoptotic Bcl-2 expression in rats treated with NTZ-200, NAC or 4-PBA when compared to MTX group (Figure 9)

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Seek urgent medical attention (call 111, 999, or go to A&E as appropriate) if you experience severe, persistent abdominal pain (which may radiate to your back and could indicate pancreatitis) or signs of dehydration from persistent vomiting

There are early signals that GLP-1s might slow how fast certain cancers spread

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