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Additionally, the constrained confirmational changes during the simulation process are confirmed by the histogram of RMSD of various ligands (Fig

Over time, these can progress to more serious neurological abnormalities

For autophagy inhibitor experiments, 3-methyladenine (3MA, Selleck, S2767) was added to each well 1-hpi to a final concentration of 5 mM

Second, they indicate minimal risk of allergic or hypersensitivity reactions, which can occur when immune responses develop against therapeutic peptides

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Environ Sci Poll Res 22:40994121 [DOI] [PubMed] [Google Scholar] Anraku M, Gebicki JM, Iohara D, Tomida H, Uekama K, Maruyama T, Hirayama F, Otagiri M (2018) Antioxidant activities of chitosans and its derivatives in in vitro and in vivo studies