retatrutide is it a glp1 vs Semaglutide and Tirzepatide: GLP-3 Facts explained Retatrutide (Triple GLP-1/GIP/Glucagon Agonist) Research

Unfortunately, this number is still on the rise, and it has been predicted that one-third of children and adolescents will be overweight or have obesity by 2050

Pharmaceuticals (Basel) 2022, 15(6)

Increased fatty acid oxidation Glucagon drives the breakdown of fat stores for energy

The NTS is the main source of endogenous GLP-1 within the brain (Holt et al., 2019)

Tirzepatide reduces alcohol drinking and relapse-like behaviours in rodents

Recommended monitoring protocol: Baseline: Full thyroid panel (TSH, free T4, free T3, TPO antibodies, thyroglobulin antibodies) plus thyroid ultrasound before starting GLP-1 therapy 6-8 weeks after starting GLP-1: Recheck TSH and free T4