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These studies revealed adverse developmental outcomes, including fetal growth abnormalities and skeletal malformations, when administered during organogenesis at clinically relevant exposures

PMID 1855720

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The most commonly mentioned effects include mild nausea in some users (typically transient), injection site reactions (redness, minor discomfort), mild headache or dizziness (uncommon), and sleep disruption with late-day dosing (reported by some users)

Tirzepatide has also been known to potentially affect (delay) the absorption of oral medications such as oral contraceptive pills