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The protein samples (40 g) were separated by 10 % SDS-polyacrylamide gel (Beyotime, Shanghai, China) electrophoresis and transferred to PVDF membranes

The results showed that Exendin-4 also promoted bone marrow-derived macrophage polarization to M2 phenotye and TGF-1 secretion via PKA-STAT3 signaling (31)

GLP-1 receptor agonists in the treatment of type 2 diabetes: state-of-the-art

Conclusions The therapeutic scope of GLP-1R agonists is expanding beyond traditional metabolic targets, highlighting its potential for headache and pain disorders

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