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The distinction between the terms bactericidal (killing bacteria) and bacteriostatic (suppressing their growth) is key here

Funding This manuscript was supported by the National Natural Science Foundation of China (Grant number: 32100925, 82027802), the Beijing Nova Program (Grant number: Z211100002121038), the Beijing Hundred Thousand and Ten Thousand Talent Project (Grant number: 2019A36), and the Beijing Municipal Health Commission (Grant number: 30301005-0019)

The Institute of Medicine states no adverse effects have been associated with excess vitamin B12 intake from food and supplements in healthy individuals. [1] However, it is important not to start a high-dosage supplement of any kind without first checking with your doctor

Clinical manifestations of hypercobalaminemia: a case report

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Avoid freezing the reconstituted solution, since freezethaw can denature the peptide