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In fact, according to Business Group on Healths 2025 Employer Health Care Strategy Survey, 79% of employers have seen an increased interest in obesity medications

Liver enzyme elevations (ALT and AST above 3 times the upper limit of normal) occurred at rates similar between orforglipron and placebo groups, with no dose-dependent pattern suggesting drug-related hepatotoxicity

Additionally, regulators such as the European Medicines Agency (EMA) have raised broader supply and safety concerns, including drug shortages due to astronomical demand

Journal Reference : Caleb A

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