Figure 3: Acetaldehyde, a byproduct of alcohol, disrupts the balance of SAM and SAH, increasing homocysteine (Hcy) conversion to methionine while reducing cysteine and glutathione (GSH) production
After reconstitution with bacteriostatic water, refrigerate at 28C and use within 8 weeks
A skeptical clinician would note that without bioequivalence data, assumed equivalence to the Phase 3 trials is an extrapolation
Trypsin (v5280, Promega, Madison, WI, United States) was then used to digest proteins into peptides (1:50 ratio of trypsin to protein (wt/wt)) and the tryptic digests were suspended in water/acetonitrile/formic acid (95:3:2) solution and analyzed in mass spectrometry
Water weight is caused by high sodium levels in the body and consumption of refined carbohydrates & sugar spikes insulin levels which increases sodium retention leading to increased water weight
When side effects indicate problems Most AOD 9604 side effects are benign and self-limiting