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(1992, Biochemical Journal) showed IGF-1 LR3 produced larger anabolic responses than native IGF-1 in dexamethasone-induced muscle catabolism in rats

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Nature PubMed Preclinical literature and narrative reviews describe pleiotropic actions including angiogenesis modulation (promotion in healing contexts and proposed inhibition in rodent corneal neovascularization models) and purported cytoprotective effects across diverse injury paradigms, but these remain unconfirmed in controlled human experiments

The KruskalWallis test was used to evaluate differences in gross morphological scores, histopathological scores, and lameness duration across all four treatment groups

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