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Similar peptides Versus tirzepatide (GLP-1/GIP dual agonist) : retatrutide surpasses tirzepatide in documented weight efficacy

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GLP-1RAs, originally developed for the treatment of type 2 diabetes mellitus (T2DM), demonstrated efficacy in promoting weight loss in both preclinical and clinical studies [12]

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The percentages of subjects who were hospitalized for HF were 4.0 and 4.2% in the lixisenatide and placebo group, respectively (HR 0.96