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NAD Diagram: Nicotinamide-containing Nucleotide (top) and Adenine-Containing Nucleotide (bottom) NAD can have an additional phosphate group added to the ribose molecule of the adenine-containing nucleotide by an enzyme called NAD kinase* to create nicotinamide adenine dinucleotide phosphate (NADP)

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We considered blood GSH level of 450 M as the cut-off for oxidative stress (Vijayalingam et al., Figure 3 shows the results of a regression analysis of diabetic patients and control subjects, segregated into four groups based on vitamin B 12 deficiency and oxidative stress