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Molecular Biology of the Cell

209 Overall, NF-B plays dual roles in autophagy regulation: it represses Bnip3 -dependent mitophagy under normoxia but promotes autophagic activation under inflammatory or immune stimuli by inducing BECN1

By the time symptoms like pins and needles, numbness in the hands and feet, or balance problems appear, the deficiency may already have progressed to neurological damage

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Additionally, Vitamin C is essential for collagen production, which keeps the skin firm

Folic acid supplementation in patients with elevated homocysteine levels