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Methionine and DAO in fibrosis regulation Metabolomic analysis in BLM-induced pulmonary fibrosis mice revealed elevated methionine in bronchoalveolar lavage fluid (BALF) and decreased levels in serum, suggesting increased methionine and proline transport to the lungs

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Together, as MTHFR is an important enzyme for folate metabolism which plays critical role in epigenetic as DNA methylation, accumulated evidence showed that global DNA methylation can be associated with MTHFR polymorphism genotypes in both healthy populations and individuals with various diseases

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