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It reduces iron from the ferric to the ferrous state in the intestine to allow absorption, is involved in the transfer of iron from plasma transferrin to liver ferritin, and regulates iron distribution and storage by preventing the oxidation of tetrahydrofolate

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This activity supports cytosolic redox balance, particularly under high glycolytic flux, and contributes to energy metabolism and reactive oxygen species (ROS) generation in metabolically active tissues 55

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