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Retatrutide has a half-life of approximately 6 days, supporting weekly dosing in research models

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"We may at some point be able to offer these again

it remains investigational under Phase 3 trials, and patients should explore NICE-approved alternatives such as Wegovy or Mounjaro through their GP

Premenopausal women with functioning ovaries typically have enough estrogen production to compensate for the loss from adipose tissue, though exceptions exist, especially with very rapid or very significant weight loss