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Choosing Your Tier Bronze: Includes the base markers and the extras

Table IV covers trials in obesity, HFpEF, and CKD

All participants had overweight or obesity (BMI 27 kg/m) and pre-existing cardiovascular disease (CVD) but notably no diabetes

Beyond its classical functions in digestion and nutrient absorption, the gut microbiota is involved in regulating immune homeostasis, modulating systemic inflammation, maintaining epithelial barrier integrity, and influencing host metabolism (Adak and Khan, 2019

However, human clinical trials are still limited, and optimal dosing in humans has not been formally established

Ninety-eight obese adults between 18 and 75 years old were randomly assigned a retatrutide dose