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Clinical study suggesting that DPP-4 inhibition blocks distal, rather than proximal, sodium reabsorption after prolonged therapy in patients with T2DM, potentially as a result of decreased inactivation of SDF1 rather than a mechanism involving GLP-1

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These outcomes are consistent with what clinical trials show for semaglutide and tirzepatide generally, so they are plausible regardless of the specific provider

And it definitely wont work the way the clinical trials showed if youre sourcing research-grade vials online and running your own protocol without monitoring