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Tirzepatide versus semaglutide (Wegovy/Ozempic) Semaglutide is a pure GLP-1 receptor agonist, while tirzepatide activates both GLP-1 and GIP receptors

However, robust clinical evidence in humans remains limited, with most published data coming from laboratory and animal studies rather than large randomized trials

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Additionally, we plan to further clarify the mechanism of Wnt pathway-mediated tumor targeting in future work by detecting key signaling molecules such as -catenin and using specific pathway inhibitors

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