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Nevertheless, their tendency toward instability in the bloodstream, the complexity of their production, and the potential for inducing undesired immune responses or toxicity remain significant concerns in their clinical development [89]

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285,286 Collectively, GLP-1 RAs integrate metabolic, anti-inflammatory, and neuroprotective mechanisms, representing a promising strategy to promote healthier aging, enhance cognitive resilience, and extend healthspan across multiple organ systems

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