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PCLS obtained from rat livers are used in most experiments, other animals including mice, miniature pigs, monkeys and dogs

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SSTRs, particularly SSTR2 and SSTR5, are highly expressed on somatotrophs in GH-secreting pituitary tumors, in which SSAs inhibits GH secretion by impeding adenylyl cyclase and decreasing cAMP levels 15,16

An Abbreviated New Drug Application (ANDA) for a generic nasal spray must demonstrate that the generic product is bioequivalent to the Reference Listed Drug (RLD)

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