Liu Z, Bao H, Cai J, Han J, Zhou L
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Oral administration of HGSD (100 mg/kg) significantly improved glucose and lipid metabolism in diabetic rats compared with pure BBR (100 mg/kg), BBR tablets (100 mg/kg), or metformin (300 mg/kg),this related to the inhibition of iPLA2/p38 MAPK pathway to decrease -cell apoptosis (Bi et al., 2022
Studies using chondrogenic cell lines or primary growth plate chondrocytes further, confirm direct actions of Ca 2+ on the cells to stimulate G protein-mediated signaling responses, and promote terminal differentiation of the cells (4447)
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